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PCM 650MG TABLET belongs to the group of mild analgesics (pain killer), and antipyretic (fever-reducing agent) used to treat mild to moderate pain including headache, migraine, toothache, menstrual period pain, osteoarthritis pain, musculoskeletal pain, and reducing fever. Pain and fever are caused by the activation of pain receptors due to the release of certain natural chemicals in our body like prostaglandin.

PCM 650MG TABLET contains ‘Paracetamol’ which prevents the release of a natural chemical (prostaglandin), causing a sensation of pain, inflammation, and fever. PCM 650MG TABLET also has an antipyretic effect and can reduce body temperature in cases of fever. PCM 650MG TABLET works by resetting the temperature-regulating centre in the brain, thus decreasing temperature in fevers caused due to illness, chemotherapy, or other reasons.

PCM 650MG TABLET is available as an over-the-counter medication. However, it is always recommended to use it after consulting a doctor. The dose and duration of the medication depend on your condition and its severity. The common side effects of PCM 650MG TABLET include agitation, nervousness, and insomnia. Everyone needs not experience the above side effects as they vary depending on their health, underlying conditions, age, weight and gender. In case of any discomfort, speak with a doctor.

Before starting PCM 650MG TABLET, please inform your doctor if you have any known allergy to paracetamol, heart, kidney or liver problems, or persistent headaches. And also, if prescribed by your doctor, ask if the medication is safe to use during pregnancy and breastfeeding.

Uses of PCM 650MG TABLET

Fever, Pain relief

Directions for Use

Swallow the tablet whole with a glass of water before or after the meals. It is recommended to take a tablet after food to avoid any gastrointestinal irritation. Do not chew, crush, or break it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time. Space the doses evenly, and take it at a fixed time for better results.


Store in a cool and dry place away from sunlight

Side Effects of PCM 650MG TABLET

Most of the side effects of PCM 650MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to a doctor. Some common side effects of PCM 650MG TABLET are liver damage, skin rashes, increased heartbeat, low platelets, and low white blood cells. Some may experience allergic skin reactions like peeling and blistering of the skin. Inform your doctor if you are allergic to paracetamol, or any other ingredients. Everyone may not experience these side-effects.

In-Depth Precautions and Warning

Drug Warning

Consult your doctor immediately, if you develop any allergic reactions such as skin rash, swelling of face/lips/tongue/throat, wheezing or shortness of breath. Do not take it if you have any known allergy to paracetamol. People with kidney diseases, liver disease, heart disease, allergic skin problems, or breathing problems should avoid taking PCM 650MG TABLET. People who are dehydrated for a long time should avoid intake of PCM 650MG TABLET. If you have a low sodium level in the body first consult with the doctor before intake of PCM 650MG TABLET. People who are heavy alcoholic drinkers (alcohol addict) should consult a doctor and avoid a PCM 650MG TABLET intake. Do not take PCM 650MG TABLET if you have persistent headache problem. PCM 650MG TABLET is not recommended for use in the children less than 2 months of age groups.

Safety Advice



Parasafe-650 Tablet 10’s and alcohol when taken together increase the chance of liver damage. Thus not recommended to be taken with alcohol.



Safe to use during pregnancy at low doses however doctor’s consultation is recommended.


It should be used only on doctor’s consultation as paracetamol passes with mothers milk to the baby.


Safe to use before driving as it doesn’t affect awareness & muscle coordination.



Paracetamol in higher doses can stop liver functioning thus should be used on the recommendation of doctors in patients with liver diseases.


It should be used by kidney patients only if the doctor has prescribed it.



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